"Our study shows that renin-producing cells are responsible for the damage," said researcher Dr María Luisa Sequeira López. "We are now focused on understanding how these cells, which are so important for protecting us from a drop in blood pressure and maintaining our well-being, undergo such changes and induce kidney damage. There is a need to identify what substances these cells make that lead to uncontrolled vessel growth."
understand why blood pressure drugs have negative effects on kidney function, researchers conducted a study on both rats and humans, which showed that these drugs can improve artery and blood vessel health in the kidneys. How do they affect
The team identified renin cells as the major culprit behind many kidney health risks. When the body is functioning properly, these cells make a hormone that regulates blood pressure levels. However, when consumers are taking medication to control their blood pressure, it creates these cells that can block healthy blood flow to the kidneys.
"It will be important to conduct prospective, randomized controlled studies to determine the extent of functional and tissue damage in patients taking medications for blood pressure control," said researcher Dr. Ariel Gomez. "It is imperative to find out what molecules these cells make so that we can combat them to prevent damage, while high blood pressure is treated with the drugs available today."