The keto diet is dangerous in the long run, although it works best in the short term

The keto diet is dangerous in the long run, although it works best in the short term

A research done on mice found that a ketogenic diet, which gets all of its calories from fat and protein and just 1% from carbs, may have positive health impacts right away but detrimental ones after roughly a week. The research, which was published in the journal Nature Metabolism, hypothesizes that the ketogenic diet may, for brief periods of time, enhance human health by reducing the risk of diabetes and inflammation. According to the researchers, the keto diet has grown in popularity as celebrities like Gwyneth Paltrow and Kim Kardashian have endorsed it as a weight-loss plan.

According to the primary author, Yale University's Vishwa Deep Dixit, the diet deceives the body into burning fat. The body behaves as if it is in a starving condition, even though it is not, and starts burning fats instead of carbs when the body's glucose level is dropped as a result of the diet's low carbohydrate content. The result of this process is an alternate fuel source known as ketone bodies. Gamma delta T-cells that defend tissue grow throughout the body when ketone bodies are burned by the body. According to Dixit, this lowers the chance of developing diabetes, decreases inflammation, and boosts metabolism.

Mice on the ketogenic diet demonstrate a decrease in blood sugar and inflammation after a week, he added. However, the researchers found that fat accumulation also takes place at the same time as fat breakdown when the body is in this "starving-not-starving" condition. After a week on the high-fat, low-carb diet, mice start to gain weight and develop diabetes because they are consuming more fat than they can burn. In the fat, "they lose the protecting gamma delta T-cells," according to Dixit.

The researchers acknowledged that long-term clinical investigations in humans are still required to support the anecdotal claims of the health advantages of keto. The mechanism behind the metabolic and immunological advantages or any possible damage to those who are overweight and pre-diabetic must be understood before such a diet may be given, according to Dixit. "Type 2 diabetes and obesity are lifestyle disorders. Diet gives individuals a means to take charge, "added he.

With the most recent studies, scientists have a better understanding of how the ketogenic diet affects the body and why it may have short-term positive effects on health. According to Yale postdoctoral researcher Emily Goldberg, "our results underscore the connection between metabolism and the immune system, and how it coordinates preservation of good tissue function."